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So it is with climate change today. As American geologist Harry Hess said in the 1960s about plate tectonics, one can quibble about the details, but the overall picture is clear.
Yet some climate-change deniers insist that the observed changes might be natural, perhaps caused by variations in solar irradiance or other forces we don't yet understand. Perhaps there are other explanations for the receding glaciers. But "perhaps" is not evidence.
The greatest scientist of all time, Isaac Newton, warned against this tendency more than three centuries ago. Writing in "Principia Mathematica" in 1687, he noted that once scientists had successfully drawn conclusions by "general induction from phenomena," then those conclusions had to be held as "accurately or very nearly true notwithstanding any contrary hypothesis that may be imagined…. "
Climate-change deniers can imagine all the hypotheses they like, but it will not change the facts nor "the general induction from the phenomena."
None of this is to say that there are no uncertainties left -- there are always uncertainties in any live science. Agreeing about the reality and causes of current global warming is not the same as agreeing about what will happen in the future. There is continuing debate in the scientific community over the likely rate of future change: not "whether" but "how much" and "how soon."
And this is precisely why we need to act today: because the longer we wait, the worse the problem will become, and the harder it will be to solve.
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